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Insight on research
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Ferroptosis Accompanied by ·OH Generation and Cytoplasmic Viscosity Increase Revealed via Dual-Functional Fluorescence Probe
Ferroptosis is a newly discovered regulated cell death process. Unlike apoptosis, ferroptosis results from the iron-dependent accumulation of lipid peroxides, which is closely associated with reactive oxygen species (ROS). Nevertheless, it is uncertain which ROS plays a key role in the lipid peroxidation during ferroptosis. Evidence has indicated that hydroxyl radical (·OH), the most active ROS, is capable of initiating lipid peroxidation. Moreover, similar to ferroptosis, the generation of ...
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New microarrays Raman sensor for lung cancer biomarker detection
Volatile organic compounds (VOCs) have been recognized as a significant endogenous signaling molecule in human exhalation and are closely associated with a number of pathophysiological processes. The profile of VOCs differs between patients with lung cancer and healthy subjects. The detection of trace VOCs in breath sampling is completely noninvasive and constitutes a potentially useful approach to screening lung cancer.
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New spectroscopic probe and its application to fluorescence imaging of hydroxyl radical
Development of new spectroscopic probes and specific imaging methods is of great importance for various biological studies. Prof. Ma’s research group at the Institute of Chemistry, Chinese Academy of Sciences (ICCAS), has been engaged in this area for more than 20 years, during which a series of new spectroscopic probes and sensing methods for bioactive species have been developed by using various chemical reactions. Based on their important results, Prof. Ma and his colleagues have been inv...
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New spectroscopic probe and its use in fluorescence imaging of monoamine oxidase A
Because of their high sensitivity and spatiotemporal resolution, excellent spectroscopic (chromogenic, fluorescent, or chemiluminescent) probes have attracted much attention. Prof. Ma’s research group at the Institute of Chemistry, Chinese Academy of Sciences, has been engaged in this field for more than two decades, during which a series of new spectroscopic probes and sensing/labeling methods for biologically active species have been developed by employing different chemical reactions. Bas...
Latest News
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2013 ACL Autumn Meeting Held
In 28th, Sep. 2013, the annual autumn meeting of ACL was held in Beijing. All the students and faculty attended the meeting. The safety knowledge lectures, scientific reports and the award ceremony were arranged in this meeting.
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ACL Obtained the Fund of “National Natural Science Foundation of China Innovative Research Team”
The project of “National Natural Science Foundation of China Innovative Research Team” was set by Natural Science Foundation of China in 2000, which is aim to support the creative research team. Such a fund to our lab is helpful to establish the new platform for the development of analytical chemistry.
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Professor Ping Yu Obtained Natural Science Fund for Excellent Young Scholars
Recently, Associate Professor Ping Yu obtained the Natural Science Fund for Excellent Young Scholars, which was supported by Natural Science Foundation of China. The total amount of this fund is ¥ 1 million. It is also the first Natural Science Fund for Excellent Young Scholars in our laboratory.
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Research achievements in ACL awarded the Science and Technology Awards of Beijing
The on-line in vivo analysis of bioactive molecules at the living animal level could reflect the chemical information change in real life process. Thus it is significant in the research of analytical chemistry and neuropathology. The Prof. Lanqun Mao’s group in ACL embarks on the research of new mechanisms and methods of analytical chemistry for living biosystems all the time.
 
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