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Insight on research
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New spectroscopic probe and its use in fluorescence imaging of tyrosinase activity
Due to the high sensitivity and high spatiotemporal resolution, the development of excellent spectroscopic (chromogenic, fluorescent, or chemiluminescent) probes has attracted much attention. Prof. Ma’s research group at the Institute of Chemistry, Chinese Academy of Sciences, has been engaged in this field for more than two decades, during which a series of new spectroscopic probes and sensing/labeling methods for biologically active species have been developed by employing different chemic...
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New advances in nitroreductase detection and cell hypoxia imaging
Hypoxia, caused by an inadequate oxygen supply, is an important feature of many diseases including solid tumors. The hypoxic status of solid tumors has been considered to be an indicator of adverse prognosis because of tumor progression toward a more malignant phenotype with increased metastatic potential and resistance to treatment. Consequently, hypoxic cells usually provide a tumor-specific targeting strategy for therapy. Because of this, developing novel methods for hypoxia detection is o...
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Significant advances in spectroscopic probes and live-cell imaging
Spectroscopic probes have been used in various fields because of their high sensitivity and great temporal and spatial sampling capability. The development of new spectroscopic probes with superior properties is important for the detection of different analytes. Prof. Ma Huimin. Dr. Shi Wen and their co-workers from CAS Key Laboratory of Analytical Chemistry for Living Biosystems have developed a series of new spectroscopic probes for bio-molecules (Chem. Commun. 2008, 1856-1858; Chem. Commun...
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Preparation of polymer nanomaterial and its application in cell imaging
Polymer based nanomaterials have received much interest due to their wide range of applications. It is particularly appealing to extend the applications in analytical chemistry for living biosystems to utilize the merits of polymer based nanomaterials. Recently, a series of stimuli-responsive polymer materials have been synthesized and studied by Qi’s group. Firstly, a kind of thermal sensitive block copolymer with fluorescent molecule has been prepared and applied in the intracellular tempe...
Latest News
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2013 ACL Autumn Meeting Held
In 28th, Sep. 2013, the annual autumn meeting of ACL was held in Beijing. All the students and faculty attended the meeting. The safety knowledge lectures, scientific reports and the award ceremony were arranged in this meeting.
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ACL Obtained the Fund of “National Natural Science Foundation of China Innovative Research Team”
The project of “National Natural Science Foundation of China Innovative Research Team” was set by Natural Science Foundation of China in 2000, which is aim to support the creative research team. Such a fund to our lab is helpful to establish the new platform for the development of analytical chemistry.
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Professor Ping Yu Obtained Natural Science Fund for Excellent Young Scholars
Recently, Associate Professor Ping Yu obtained the Natural Science Fund for Excellent Young Scholars, which was supported by Natural Science Foundation of China. The total amount of this fund is ¥ 1 million. It is also the first Natural Science Fund for Excellent Young Scholars in our laboratory.
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Research achievements in ACL awarded the Science and Technology Awards of Beijing
The on-line in vivo analysis of bioactive molecules at the living animal level could reflect the chemical information change in real life process. Thus it is significant in the research of analytical chemistry and neuropathology. The Prof. Lanqun Mao’s group in ACL embarks on the research of new mechanisms and methods of analytical chemistry for living biosystems all the time.
 
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