HOME INTRODUCTION STAFF RESEARCH RECRUITMENT CONTACT US 中文
Location:Home > Fuyi Wang > Publications
 
    Home
    Prof. Fuyi Wang
    Members
    Research
    Publications
    Photo Gallery
    News
    中文
 
Publications

Academic Publications and Patents

Academic Publications

--- 2019 --- 

  

  • Luyu Qi, Qun Luo, Yanyan Zhang, Feifei Jia, Yao Zhao*, Fuyi Wang*, Advances in Toxicological Research of the Anticancer Drug Cisplatin, Chem. Res. Toxicol., 2019, 32(8), 1469-1486
  • Wenjuan Zeng,Yanyan Zhang,Wei Zheng,Qun Luo, Juanjuan Han, Jian’an Liu, Yao Zhao, Feifei Jia, Kui Wu,* Fuyi Wang*, Discovery of Cisplatin Binding to Thymine and Cytosine on a Single-Stranded Oligodeoxynucleotide by High Resolution FT-ICR Mass Spectrometry, Molecules, 2019, 24(10), 1852
  • Wenjuan Zeng, Zhifeng Du, Qun Luo, Yao Zhao, Yuanyuan Wang, Kui Wu, Feifei Jia, Yanyan Zhang,* and Fuyi Wang*, Proteomic Strategy for Identification of Proteins Responding to Cisplatin-Damaged DNA. Anal. Chem. 2019, 91, 6035-6042.
  • Yanyan Zhang, Jun-Gang Wang, Xiaofei Yu, Donald R. Baer, Yao Zhao, Lanqun Mao, Fuyi Wang,* Zihua Zhu*. Potential-Dynamic Surface Chemistry Controls the Electrocatalytic Processes of Ethanol Oxidation on Gold Surfaces. ACS Energy Lett., 2019, 4, 215-221.
  • Yanyan Zhang, Wenjuan Zeng, Liuqin Huang, Wen Liu, Endong Jia, Yao Zhao, Fuyi Wang*, Zihua Zhu*. In Situ Liquid Secondary Ion Mass Spectrometry: A Surprisingly Soft Ionization Process for Investigation of Halide Ion Hydration. Anal. Chem., 2019, 91(11), 7039-7046.
  • Yumiao Han, Wei Guo, Wei Zheng, Qun Luo, Kui Wu, Yao Zhao*, Fuyi Wang*, Mass spectrometric quantification of the binding ratio of metalbased anticancer complexes with protein thiols, Rapid Commun Mass Spectrom., 2019, 33, 951–958.
  • Yu Lin, Jie Wang, Wei Zheng, Qun Luo, Kui Wu, Jun Du,* Yao Zhao*, Fuyi Wang*,  Organometallic ruthenium anticancer complexes inhibit human peroxiredoxin I activity by binding to and inducing oxidation of its catalytic cysteine residue, Metallomics, 2019,11, 546

--- 2018 ---   

  • Yanyan Zhang, Mao Su, Xiaofei Yu, Yufan Zhou, Jungang Wang, Ruiguo Cao, Wu Xu, Chongmin Wang, Donald R. Baer, Oleg Borodin, Kang Xu, Yanting Wang, Xue-Lin Wang, Zhijie Xu,* Fuyi Wang,* Zihua Zhu*. Investigation of Ion-Solvent Interactions in Nonaqueous Electrolytes Using in Situ Liquid SIMS. Anal. Chem., 2018, 90 (5), 3341-3348.
  • Yiyu Cheng, Wenjuan Zeng, Yang Cheng, Jishuai Zhang, Tao Zou, Kui Wu*, Fuyi Wang*, Selective binding of an organoruthenium complex to Grich human telomeric sequence by tandem mass spectrometry, Rapid Commun Mass Spectrom. 2018, 32, 2152-2158
  • Suyan Liu, Aihua Liang ,Kui Wu*, Wenjuan Zeng, Qun Luo, Fuyi Wang*, Binding of Organometallic Ruthenium Anticancer Complexes to DNA: Thermodynamic Base and Sequence Selectivity, Int. J. Mol. Sci., 2018, 19(7), 2137
  • Jun Du, Yuanyuan Wei, Yao Zhao*, Fengmin Xu, Yuanyuan Wang, Wei Zheng, Qun Luo, Ming Wang, Fuyi Wang*, A Photoactive Platinum(IV) Anticancer Complex Inhibits Thioredoxin–Thioredoxin Reductase System Activity by Induced Oxidization of the Protein, Inorg. Chem., 2018, 57(9), 5575-5584
  • Yang Zhang, Qun Luo, Wei Zheng,* Zhaoying Wang, Yu Lin, Erlong Zhang,   Shuang Lü,   Junfeng Xiang, Yao Zhao, Fuyi Wang*, Luminescent cyclometallated platinum(ii) complexes: highly promising EGFR/DNA probes and dual-targeting anticancer agents, Inorg. Chem. Front., 2018, 5, 413-424

--- 2017 ---   

  

  •  Y. Y. Wang, Z. F. Du,* W.  Zheng, K. Wu, D. C. Xu, Q. Luo, Y.  Zhao, J. J. Han, Y. Z. Liu, F. Y. Wang,* Deciphering of Interactions between Platinated DNA and HMGB1 by Hydrogen/Deuterium Exchange Mass Spectrometry, Dalton Trans. 2017, 46, 6133-6484
  •  Kui Wu, Qun Luo, Yao Zhao, Wei Zheng, Fuyi Wang,* Investigations of molecular mechanism of action of metal-based anticancer complexes by mass spectrometry,   SCIENTIA SINICA Chimica 2017, 47(2), 233-248
  •  Kui Wu,  Feifei Jia, Wei Zheng, Qun Luo, Yao Zhao, Fuyi Wang,* Visualization of metallodrugs in single cells by secondary ion mass spectrometry imaging, J. Biol. Inorg. Chem. 2017, 653-661
  • Wei Zheng, Yao Zhao*, Qun Luo, Yang Zhang, Kui Wu, Fuyi Wang*. Multi-Targeted Anticancer Agents, Current Topics in Medicinal Chemistry, 2017, 17(28), 3084-3098

--- 2016 ---  

  • J. Du, Y. Kang, Y. Zhao*, W. Zheng, Y. Zhang, Y. Lin, Z. Wang, Y. Wang, Q. Luo, K. Wu and F.-Y. Wang*, Synthesis, Characterization, and in Vitro Antitumor Activity of Ruthenium(II) Polypyridyl Complexes Tethering EGFR-Inhibiting 4-Anilinoquinazolines, Inorg. Chem., 2016, 55, 4595-4605.
  •  Yulong Jin, Yunfeng Xie, Kui Wu, Yanyan Huang,* Fuyi Wang,* Rui Zhao,* Probing the Dynamic Interaction between Damaged DNA and a Cellular Responsive Protein Using a Piezoelectric Mass Biosensor, ACS Appl. Mater. Interfaces 2017, 9, 8490-8497
  •  W. Zheng, Y. Zhao*, Q. Luo, Y. Zhang, K. Wu and F.-Y. Wang*, Rational design of multi-targeting ruthenium- and platinum-based anticancer complexes, Sci. China Chem., 2016, 59, 1240-1249.
  • L. Li, W. Guo, K. Wu*, X. Wu, L. Zhao, Y. Zhao, Q. Luo, Y. Wang, Y. Liu, Q. Zhang* and F.-Y. Wang, A comparative study on the interactions of human copper chaperone Cox17 with anticancer organoruthenium(II) complexes and cisplatin by mass spectrometry, J. Inorg. Biochem., 2016, 161, 99-106.
  • Z. Wang, J. Liu, Y. Zhou, J. J. Neeway, D. K. Schreiber, J. V. Crum, J. V. Ryan, X.-L. Wang, F.-Y. Wang* and Z. Zhu*, Nanoscale imaging of Li and B in nuclear waste glass, a comparison of ToF-SIMS, NanoSIMS, and APT, Surf. Interface Anal., 2016, 48, 1392–1401.
  •  L. Li, W. Guo, K. Wu*, Y. Zhao, Q. Luo, Q. Zhang, J. Liu, S. Xiong and F.-Y. Wang*, Identification of binding sites of cisplatin to human copper chaperone protein Cox17 by high-resolution FT-ICR-MS, Rapid Commun. Mass Spectrom., 2016, 30, 168-172.
  •  J. Qiao#, J. Y. Kim#, Y. Y. Wang, L. Qi*, F. Y. Wang and M. H. Moon*, Trypsin immobilization in ordered porous polymer membranes for effective protein digestion, Anal. Chim. Acta, 2016, 906, 156-164.
  •  X. Wang, J. Xu*, Y. Wang, F.-Y. Wang and Y. Chen*, A universal strategy for direct immobilization of intact bioactivity-conserved carbohydrates on gold nanoparticles, RSC Advances, 2016, 6, 85333-85339.

                                                                         --- 2015 --- 

  •  J. Du, E. Zhang, Y. Zhao*, W. Zheng, Y. Zhang, Y. Lin, Z. Wang, Q. Luo, K. Wu and F.-Y. Wang*, Discovery of a dual-targeting organometallic ruthenium complex with high activity inducing early stage apoptosis of cancer cells, Metallomics, 2015, 7, 1573-1583.
  •  Y. Lin, Y. Huang, W. Zheng, K. Wu, Q. Luo, Y. Zhao, S. Xiong and F.-Y. Wang*, Quantification of bindings of organometallic ruthenium complexes to GSTπ by mass spectrometry, J. Inorg. Biochem., 2015, 146, 44-51.
  • Z. Wang, B. Liu, E. W. Zhao, K. Jin, Y. Du, J. J. Neeway, J. V. Ryan, D. Hu, K. H. L. Zhang, M. Hong, S. Le Guernic, S. Thevuthasan, F.-Y. Wang* and Z. Zhu*, Argon Cluster Sputtering Source for ToF-SIMS Depth Profiling of Insulating Materials: High Sputter Rate and Accurate Interfacial Information. J. Am. Soc. Mass. Spectrom. 2015, 26, 1283-1290.

     

--- 2014 ---  

  

  • S. Y. Liu, K. Wu,* W. Zheng, Y. Zhao, Q. Luo, S. X. Xiong, F. Y. Wang,* Identification and Discrimination of Binding Sites of an Organoruthenium Anticancer Complex to Single-Stranded Oligonucleotides by Mass Spectrometry, Anlayst, 2014, 10.1039/c4an00807c

  • Z. Y. Wang, K. Jin, Y. W. Zhang, F. Y. Wang,* Z. H. Zhu,* ToF-SIMS depth profiling of insulating samples: interlaced mode or non-interlaced mode, Surf. Interface Anal. 2014, DOI 10.1002/sia.5419  

  • W. J. Xia, Z. F. Du, Q. F. Cui, H. Dong, F. Y. Wang*, P. Q. He, Y. C. Tang,* Biosurfactant produced by Novel Pseudomonas sp. WJ6 with 3 Biodegradation of n-Alkanes and Polycyclic Aromatic Hydrocarbons, J. Hazard. Mater., 2014, 276C, 489-498

  • G. J. Zhai, X. Y. Wu, Q. Luo, K. Wu, Y. Zhao, Y. L. Min, J. A. Liu, X. S. Xiong, Y. Q. Feng, L. P. Yang,* F. Y. Wang,* Absolute Quantification of Serum Phosphopeptides by Mass Spectrometry Coupled to Titania Coated Magnetic Mesoporous Silica Microsphere Enrichment, Talanta, 2014, 125, 411–417

  • L. Y. Ji, W. Zheng, Y. Lin, X. L. Wang, S. , X. Hao, Q. Luo,* X. C. Li, L. Yang, F. Y. Wang,* Novel Ruthenium Complexes Ligated with 4-Anilinoquinazoline Derivatives: Synthesis, Characterisation and Preliminary Evaluation of Biological Activity, Eur. J. Med. Chem. 2014, 77, 110-120

  • Z. Du, Q. Luo, L. Yang, T. Bing, X. Li, W. Guo, K. Wu, Y. Zhao, S. Xiong, D. Shangguan, F.-Y. Wang*, Mass Spectrometric Proteomics Reveals that Nuclear Protein Positive Cofactor PC4 Selectively Binds to Cross-Linked DNA by a trans-Platinum Anticancer Complex, J. Am. Chem. Soc. 2014, 136, 2948-2951. 
  • Z. Y. Xi, W. Guo, C. L. Tian,* F. Y. Wang,* Y. Z. Liu,* Copper binding modulates the platination of human copper chaperone Atox1 by antitumor trans-platinum complexes, Metallomics 2014, 6, 491-497

  • B. Jin, X. Zhang, W. Zheng, X. J. Liu, C. Qi, F. Y. Wang, D. H. Shangguan,* Fluorescence Light-Up Probe for Parallel GQuadruplexes, Anal. Chem. 2014, 86, 943?952 

  • B. Jin, X. Zhang, W. Zheng, X. J. Liu, J. Zhou, N. Zhang, F. Y. Wang, D. H. Shangguan, Dicyanomethylene-Functionalized Squaraine as a Highly Selective Probe for Parallel G-Quadruplexes, Anal. Chem. 2014, 86, 7063?7070 

     

 

 

--- 2013 ---  

  

  • Y. Zhao, N. J. Farrer, H. Li, J. S. Butler, R. J. McQuitty, A. Habtemariam, F.-Y. Wang*, P. J. Sadler*, De Novo Generation of Singlet Oxygen and Ammine Ligands by Photoactivation of a Platinum Anticancer Complex, Angew. Chem. Int. Ed. 2013, 52, 13633-13637.

  • W. Zheng, Q. Luo, Y. Lin, Y. Zhao, X. Wang, Z. Du, X. Hao, Y. Yu, S. Lu, L. Ji, X. Li, L. Yang, F.-Y. Wang*, Complexation with organometallic ruthenium pharmacophores enhances the ability of 4-anilinoquinazolines inducing apoptosis, Chem. Commun. 2013, 49, 10224-10226.

  • K. Wu, S. Liu, Q. Luo, W. Hu, X. Li, F.-Y, Wang*, R. Zheng, J. Cui, P. J. Sadler, J. Xiang, Q. Shi, S. Xiong, Thymines in Single-Stranded Oligonucleotides and G-Quadruplex DNA Are Competitive with Guanines for Binding to an Organoruthenium Anticancer Complex, Inorg. Chem. 2013, 52 (19), 11332-11342.

  • Y. Lin, Y-D Huang, W. Zheng, F.-Y. Wang*, A. Habtemariam, Q. Luo, X.-C. Li, K. Wu, P. J. Sadler, S.-X. Xiong, Organometallic ruthenium anticancer complexes inhibit human glutathione-S-transferase π, J Inorganic Biochem, 2013, 128, 77-84.

  • W. Guo, W. Zheng, Q. Luo, X. Li, Y. Zhao, S. Xiong, F.-Y. Wang,* Transferrin Serves As a Mediator to Deliver Organometallic Ruthenium(II) Anticancer Complexes into Cells, Inorg. Chem. 2013, 52, 5328-5338.

  • G.-B. Ge, C.-Z. Ai, W.-B. Hu, J. Hou, L.-L. Zhu, G.-Y. He, Z.-Z. Fang, S.-C. Liang, F.-Y. Wang*, L. Yang*, The role of serum albumin in the metabolism of Boc5: molecular identification, species differences and contribution to plasma metabolism, Eur. J. Pharm. Sci., 2013, 48, 360-369.

  • K. Wu, W. Hu, Q. Luo, X. Li, S. Xiong, P. Sadler, F.-Y. Wang*, Competitive binding sites of a ruthenium arene anticancer complex on oligonucleotides studied by mass spectrometry: ladder-sequencing vs top-down, J. Am. Soc. Mass. Spectrom., 2013, 24, 410-420.

  • F.-Y. Wang, J. Xu, K. Wu, S. K. Weidt, C. L. Mackay, P. R. R. Langridge-Smith, P. J. Sadler*, Competition between glutathione and DNA oligonucleotides for ruthenium(II) arene anticancer complexes, Dalton Trans. 2013, 42, 3188-3195.

  • S. Lü, W. Zheng, L. Ji, Q. Luo, X. Hao, X. Li, F.-Y. Wang*, Synthesis, characterization, screening and docking analysis of 4-anilinoquinazoline derivatives as tyrosine kinase inhibitors, Eur. J. Med. Chem.2013, 61, 84-94.

 

 

--- 2012 ---

 

    •  X. Li, Z. Zhao, W. Hu, F.-Y. Wang,* Interactions between cisplatin and proteins, and their pharmacological implications in Cisplatin: Pharmacology, Clinical Uses and Adverse Effects, Eds: Toshiko Kojima and Yoko Moria, pp75-95, Nove Science Publishers, Inc, U.S.A., 2012.
    • Y. Jin, Y. Huang*, Y. Xie, W. Hu, F.-Y. Wang, G. Liu, R. Zhao*, Cyclic interconversion of methionine containing peptide between oxidized and reduced phases monitored by reversed-phase HPLC and ESI-MS/MS, Talanta 2012, 89, 531-536.
    •  L. Ji, J.-H. Wu, Q. Luo, X. Li, W. Zheng, G. Zhai, F.-Y. Wang*, S. Lü, Y.-Q. Feng*, J. Liu, S. Xiong, Quantitative Mass Spectrometry Combined with Separation and Enrichment of Phosphopeptides by Titania Coated Magnetic Mesoporous Silica Microspheres for Screening of Protein Kinase Inhibitors, Anal. Chem. 2012, 84, 2284-2291.
    • K. Wu, Q. Luo, W. Hu, X. Li, F.-Y. Wang*, S. Xiong, P. J. Sadler*, Mechanism of Interstrand Migration of Organoruthenium Anticancer Complexes within a DNA Duplex, Metallomics, 2012, 4, 136-148

     

    --- 2011---

     

    • S. Lü, Q. Luo, X. Hao, X. Li, L. Ji, W. Zheng, F.-Y. Wang*, Synthesis and docking study of 2-phenylaminopyrimidine Abl tyrosine kinase inhibitors, Bioorg. Med. Chem. Lett. 2011, 21, 6964-6968.
    • Y. Han, Q. Luo, X. Hao, X. Li, F.-Y. Wang*, W. Hu, K. Wu, S. Lu, P. J. Sadler*, Reactions of an organoruthenium anticancer complex with 2-mercaptobenzanilide - a model for the active-site cysteine of protein tyrosine phosphatase 1B, Dalton Trans. 2011, 40, 11519-11529.
    • W. Hu, Q. Luo, K. Wu, X. Li, F.-Y Wang*, Y. Chen, X. Ma, J. Wang, J. Liu, S. Xiong, P. J. Sadler*, The anticancer drug cisplatin can cross-link the interdomain zinc site on human albumin, Chem. Commun. 2011, 47, 6006-6008.
    •  W. Hu, J. Liu, Q. Luo*, Y. Han, K. Wu, S. Lv, S. Xiong, F.-Y. Wang,* Elucidation of the Binding Sites of Sodium Dodecyl Sulfate to b-Lactoglobulin Using Hydrogen/Deuterium Exchange Mass Spectrometry Combined with Docking Simulation, Rapid Commun. Mass Spectrom. 2011, 25, 1429-1436.
    • G. Zhang, W. Hu, Z. Du, S. Lv, W. Zheng, Q. Luo, X. Li, K. Wu, Y. Han, F.-Y. Wang*, A Comparative Study on Interactions of Cisplatin and Ruthenium Arene Anticancer Complexes with Metallothionein using MALDI-TOF-MS, Intl. J. Mass Spectrom. 2011, 307, 79-84
    •  C. Yao, L. Qi*, W. Hu, F.-Y Wang, G. Yang, Immobilization of trypsin on sub-micron skeletal polymer monolith, Ana. Chim. Acta, 2011, 692, 131-137.
    •  Q. Luo, D. Wu, S. Liu, D. Tang*, Y. Huang, X. Liu, F.-Y. Wang*, R. Wang, G. Wu*, The formation of thymidine-based t-tetramers with remarkable structural and metal ion size effects, Org. Biomol. Chem., 2011, 9,1030-1033

     

    --- 2010 ---

     

    •  S. Lv, Q. Luo, X. Li, K. Wu, J. Liu, S. X. Xiong, Y. Feng, F.-Y. Wang*, Inhibitor Screening of Protein Kinases Using MALDI-TOF MS Combined with Separation and Enrichment of Phosphopeptides by TiO2 Nanoparticle Deposited Capillary Column, Analyst, 2010, 135, 2858-2863.
    • X. Wei, L. Qi*, J. Qiao, C. Yao, F.-Y. Wang, Y. Chen, Assay of vitamin B in urine by capillary electrochromatography with methacrylate-based monolithic column, Electrophoresis, 2010, 31(19), 3227-3232.
    •  C. Yao, L. Qi*, J. Qiao, H. Zhang, F.-Y. Wang, G. Yang, Y. Chen, High-performance affinity monolith chromatography for enantiomer separation and determination of enzyme kinetic constant, Talanta, 2010, 82(4), 1332-1337.
    •  X. Wei, L. Qi*, J. Tan, R. Liu, F.-Y. Wang, A colorimetric sensor for determination of cysteine by carboxymethyl cellulose functionalized gold nanoparticle, Anal. Chim. Acta, 2010, 671, 80-84.
    • C. Yao, L. Qi*, G. Yang, F.-Y. Wang, Preparation of sub-micron skeletal monolith with high capacity for liquid chromatography, J. Sep. Sci., 2010, 33, 475-483.
    •  H. Liu*, J. A. Parkinson, J. Bella, F.-Y. Wang, P. J. Sadler*, Penetrative DNA intercalation and G-base selectivity of an organometallic tetrahydroanthracene RuII anticancer complex, Chem. Sci., 2010, 1, 258-270.
    •  胡文兵,汪福意*,质谱在金属抗肿瘤药物与蛋白质相互作用研究中的应用(邀请综述),质谱学报,201031354-361.

     

    --- 2009 ---

     

    • X. Wei, L. Qi, G. Yang, F.-Y. Wang*, Preparation and characterization of monolithic column by grating pH-responsive polymer, Talanta, 2009, 79, 739-745
    •  D. Tang*, D. Wu, Q. Luo, W. Hu, F.-Y. Wang*, S. Liu, X. Liu, Q. Fan, Single-molecule behavior of dendritic poly(ethylene glycol) structures towards lithium ions, Chem. Eur. J. 2009, 15, 10352-10355.
    • Y. Wang, F. Li, Y. Han, F.-Y. Wang, H. Jiang*, Folding and aggregation of cationic oligo(aryl-triazole)s in aqueous solution, Chem. Eur. J., 2009, 15, 9424-9433.
    •  W. Hu, Q. Luo, X. Ma, K. Wu, J. Liu, Y. Chen, S. Xiong, J. Wang*, P. J. Sadler*, F.-Y. Wang,* Arene control over thiolate to sulfinate oxidation in albumin by organometallic ruthenium anticancer complexes, Chem. Eur. J. 2009, 15, 6586-6594.
    •  F.-Y. Wang*, A. Habtemariam, E. P. L. van der Geer, R. J. Deeth, R. Gould, S. Parsons, P. J. Sadler,* Synthesis, characterization and reaction pathway for the formation of a GMP adduct of a cytotoxic thiocyanato ruthenium arene complex, J. Biol. Inorg. Chem., 2009, 14, 1065-1076.
    • F.-Y. Wang*, W.B. Hu, Q. Luo, X.Y. Ma, J.P. Wang, P.J. Sadler*, Arene-controlled binding of organoruthenium anticancer complexes to albumin and Ru-induced oxidation of Cys34 Thiol, J. Biol. Inorg. Chem. 2009, 14(Supp1), S235.

     

    --- 2008 ? 2001 ---

     

    • F.-Y. Wang, S. Weidt, J. Xu, C. L. Mackay, P. R. R. Langridge-Smith, P. J. Sadler, Identification of clusters from reactions of ruthenium arene anticancer complex with glutathione using nanoscale liquid chromatography Fourier transform ion cyclotron mass spectrometry combined with 18O-labelling, J. Am. Soc. Mass Spectrom. 2008, 19, 544-549
    •  H. K. Liu, S. J. Berners-Price, F.-Y. Wang, J. A. Parkinson, J. Xu, J. Bella, P. J. Sadler*, Diversity in G-selective DNA binding modes for an organometallic ruthenium arene complex, Angew. Chem. Int. Ed. 2006, 45, 8153-8156
    • H. K. Liu, F.-Y. Wang, J. A. Parkinson, J. Bella, P. J. Sadler*, Ruthenation of duplex and single-stranded d(CGGCCG) by organometallic anticancer complexes, Chem. Eur. J. 2006, 12, 6151-6165
    •  F.-Y. Wang, A. Habtemariam, E. P. L. van der Geer, R. Fernández, M. Melchart, R. J. Deeth, R. Aird, S. Guichard, F. P. A. Fabbiani, P. Lozano-Casal, I. D. H. Oswald, D. I. Jodrell, S. Parsons, P. J. Sadler, Controlling ligand substitution reactions of organometallic complexes: tuning cancer cell cytotoxicity, Proc. Natl. Acad. Sci. U. S. A. 2005, 102, 18269-18274.
    • F.-Y. Wang, J. Xu, A. Habtemariam, J. Bella, P. J. Sadler*, Competition between glutathione and guanine for a ruthenium(II) arene anticancer complex: detection of a sulfenato intermediate. J. Am. Chem. Soc. 2005, 127, 17734-17743.
    • F.-Y. Wang, J. Bella, J. A. Parkinson, P. J. Sadler*, Competitive reactions of a ruthenium arene anticancer complex with histidine, cytochrome c and an oligonucleotide. J. Biol. Inorg. Chem. 2005, 10, 147-55.
    •  I. W. McNae, K. Fishburne, A. Habtemariam, T. M. Hunter, M. Melchart, F.-Y. Wang, M. D. Walkinshaw, P. J. Sadler*, Half-sandwich arene ruthenium(II)-enzyme complex. Chem. Commun. 2004, 1786-1787.
    •  F.-Y Wang, H. M. Chen, S. Parsons, I. D. H. Oswald, J. E. Davidson, P. J. Sadler*, Kinetics of aquation and anation of ruthenium(II) arene anticancer complexes, acidity and X-ray structures of aqua adducts. Chem. Eur. J. 2003, 9, 5810-5820.
    • R. Fernandez, M. Melchart, E. Van Der Geer, F.-Y. Wang, A. Habtemariam, P. J. Sadler*, Ruthenium(II) arene anticancer complexes: Selective recognition of nucleobases and control of hydrolysis rates. J. Inorg. Biochem. 2003, 96, 130-130.
    • H. M. Chen, J. A. Parkinson, O. Novakova, J. Bella, F. Y. Wang, A. Dawson, R. Gould, S. Parsons, V. Brabec, P. J. Sadler*, Induced-fit recognition of DNA by organometallic complexes with dynamic stereogenic centers. Proc. Natl. Acad. Sci. U. S. A. 2003, 100, 14623-14628.
    • F. Y. Wang, B. Hu, Z. C. Jiang, Y. L. Wu, Study on the chemical modification of acetylacetone in graphite furnace atomic absorption spectrometry determination of trace aluminium. Anal. Lett. 2002, 35, 2593-2602.
    • F. Y. Wang, H. M. Chen, J. A. Parkinson, P. D. Murdoch, P. J. Sadler*, Reactions of a ruthenium(II) arene antitumor complex with cysteine and methionine. Inorg. Chem. 2002, 41, 4509-4523.

     

    --- 2000 and before ---

     

    • H. Z. Liu, F. Y. Wang, Z. C. Jiang, Study on adsorption properties of cinchonine loaded resin to Mo and V by ICP-AES. Anal. Lett. 2000, 33, 2021-2029.
    • F. Y. Wang, Z. C. Jiang, T. Y. Peng, Use of polytetrafluoroethylene slurry for silica matrix removal in ETAAS direct determination of trace cobalt and nickel in silicon dioxide powder. J. Anal. At. Spectrom. 1999, 14, 963-966.
    •  F. Y. Wang, Z. C. Jiang, B. Hu,T. Y. Peng, Comparative studies on chemical modification of polytetrafluoroethylene slurry in ETV-ICP-AES and ETAAS. J. Anal. At. Spectrom. 1999, 14, 1619-1624.
    •  F. Y. Wang, Z. C. Jiang, Direct determination of cadmium in solid biological materials by slurry sampling electrothermal atomic absorption spectrometry with polytetrafluoroethylene as a chemical modifier. Anal. Chim. Acta 1999, 391, 89-94.
    •  汪福意, 江祖成,电热原子吸收光谱直接分析固体样品(综述),分析科学学报,2001, 17, 245
    •  汪福意,江祖成,聚四氟乙烯修饰悬浮体进样电热原子吸收光谱直接分析固体样品中的金属铬,分析科学学报,1999, 15, 111-114.
    • F.-Y. Wang, Z. C. Jiang, study of the determination of trace amounts of chromium by electrothermal atomic absorption spectrometry with a poly(tetrafluoroethylene) slurry as a chemical modifier. J. Anal. At. Spectrom. 1998, 13, 539-542.

     

     

    Patents

    1.       汪福意,韩玉苗,罗群,郑伟,吴魁,李鲜婵,抑制蛋白酪氨酸磷酸酶1B活性的含钌配合物及其制备方法和蛋白酪氨酸磷酸酶1B抑制剂,中国发明专利申请号:201210103485.8

    2.       汪福意,罗群,纪丽云,郑伟,吕爽,李鲜婵,一种抑制肿瘤细胞增殖的喹唑啉衍生物/喹唑啉配合物蛋白激酶抑制剂及它们的制备方法,PCT发明专利申请号:PCT/CN2011/081453

    3.       汪福意,罗群,纪丽云,郑伟,吕爽,一种喹唑啉衍生物蛋白激酶抑制剂,中国发明专利申请号:201010521382.4

    4.       汪福意,罗群,吕爽,纪丽云,胡文兵,吴魁,韩玉苗,一种酪氨酸蛋白激酶抑制剂及其制备方法,中国发明专利公开号:CN101890018A

    5.       汪福意,罗群,吕爽,吴魁,胡文兵,纪丽云,韩玉苗,有机金属钌抗肿瘤化合物,中国发明专利公开号:CN101891627A

     

     
  • W. Zheng, Q. Luo, Y. Lin, Y. Zhao, X. Wang, Z. Du, X. Hao, Y. Yu, S. Lu, L. Ji, X. Li, L. Yang, F.-Y. Wang*, Complexation with organometallic ruthenium pharmacophores enhances the ability of 4-anilinoquinazolines inducing apoptosis, Chem. Commun. 2013, 49, 10224-10226.
  • K. Wu, S. Liu, Q. Luo, W. Hu, X. Li, F.-Y, Wang*, R. Zheng, J. Cui, P. J. Sadler, J. Xiang, Q. Shi, S. Xiong, Thymines in Single-Stranded Oligonucleotides and G-Quadruplex DNA Are Competitive with Guanines for Binding to an Organoruthenium Anticancer Complex, Inorg. Chem. 2013, 52 (19), 11332-11342
  • Y. Lin, Y-D Huang, W. Zheng, F.-Y. Wang*, A. Habtemariam, Q. Luo, X.-C. Li, K. Wu, P. J. Sadler, S.-X. Xiong, Organometallic ruthenium anticancer complexes inhibit human glutathione-S-transferase π, J Inorganic Biochem, 2013, 128, 77-84
  • W. Guo, W. Zheng, Q. Luo, X. Li, Y. Zhao, S. Xiong, F.-Y. Wang,* Transferrin Serves As a Mediator to Deliver Organometallic Ruthenium(II) Anticancer Complexes into Cells, Inorg. Chem. 2013, 52, 5328-5338.
  • G.-B. Ge, C.-Z. Ai, W.-B. Hu, J. Hou, L.-L. Zhu, G.-Y. He, Z.-Z. Fang, S.-C. Liang, F.-Y. Wang*, L. Yang*, The role of serum albumin in the metabolism of Boc5: molecular identification, species differences and contribution to plasma metabolism, Eur. J. Pharm. Sci., 2013, 48, 360-369.  
  • K. Wu, W. Hu, Q. Luo, X. Li, S. Xiong, P. Sadler, F.-Y. Wang*, Competitive binding sites of a ruthenium arene anticancer complex on oligonucleotides studied by mass spectrometry: ladder-sequencing vs top-down, J. Am. Soc. Mass. Spectrom., 2013, 24, 410-420.
  • F.-Y. Wang, J. Xu, K. Wu, S. K. Weidt, C. L. Mackay, P. R. R. Langridge-Smith, P. J. Sadler*, Competition between glutathione and DNA oligonucleotides for ruthenium(II) arene anticancer complexes, Dalton Trans. 2013, 42, 3188-3195.
  • S. Lü, W. Zheng, L. Ji, Q. Luo, X. Hao, X. Li, F.-Y. Wang*, Synthesis, characterization, screening and docking analysis of 4-anilinoquinazoline derivatives as tyrosine kinase inhibitors, Eur. J. Med. Chem. 2013, 61, 84-94.
  •  
  • Y. Lin, Y. Huang, W. Zheng, K. Wu, Q. Luo, Y. Zhao, S. Xiong and F.-Y. Wang*, Quantification of bindings of organometallic ruthenium complexes to GSTπ by mass spectrometry, J. Inorg. Biochem., 2015, 146, 44-51.
  • Y. Zhang, W. Zheng*, Q. Luo, Y. Zhao, E. Zhang, S. Liu and F.-Y. Wang*, Dual-targeting organometallic ruthenium(II) anticancer complexes bearing EGFR-inhibiting 4-anilinoquinazoline ligands, Dalton Trans., 2015, 44, 13100-13111.
  •  Z. Wang, B. Liu, E. W. Zhao, K. Jin, Y. Du, J. J. Neeway, J. V. Ryan, D. Hu, K. H. L. Zhang, M. Hong, S. Le Guernic, S. Thevuthasan, F.-Y. Wang* and Z. Zhu*, Argon Cluster Sputtering Source for ToF-SIMS Depth Profiling of Insulating Materials: High Sputter Rate and Accurate Interfacial Information. J. Am. Soc. Mass. Spectrom. 2015, 26, 1283-1290. 
  • Y. Zhang, W. Zheng*, Q. Luo, Y. Zhao, E. Zhang, S. Liu and F.-Y. Wang*, Dual-targeting organometallic ruthenium(II) anticancer complexes bearing EGFR-inhibiting 4-anilinoquinazoline ligands, Dalton Trans., 2015, 44, 13100-13111.
         
      Copyright © CAS Key Laboratory of Analytical Chemistry for Living Biosystems
    Zhongguancun North First Street 2,100190 Beijing, PR China