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Prof Qun Luo
 
 Date: 11-08-2013  Page Views:
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Dr Qun Luo, Associate Professor

Date of Birth: Apr, 1970.

Tel: 010-62529069

Mobil: 13520735629

Email: qunluo@iccas.ac.cn

 

 

Professional Qualifications

 Member of the Chinese Society of Chemistry.

 

Selective Publications

  

  • L. Qi, Q. Luo, Y. Zhang, F. Jia, Y. Zhao*, F. Wang*, Advances in Toxicological Research of the Anticancer Drug Cisplatin, Chem. Res. Toxicol. 2019, 32(8), 1469-1486.
  • Y. Lin, J. Wang, W. Zheng, Q. Luo, K. Wu, J. Du,* Y. Zhao *,  F. Wang*, Organometallic ruthenium anticancer complexes inhibit human peroxiredoxin I activity by binding to and inducing oxidation of its catalytic cysteine residue, Metallomics, 2019, 11, 546-555. 
  • W. Zeng, Y. Zhang, W. Zheng, Q. Luo, J. Han, J. Liu, Y. Zhao, F. Jia, K. Wu*, and F. Wang*, Discovery of Cisplatin Binding to Thymine and Cytosine on a Single-stranded Oligodeoxynucleotide by High Resolution FT-ICR Mass Spectrometry, Molecules, 2019, 24, 1852.
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  • J. Du, Y. Y. Wei, Y. Zhao*, F. M. Xu, Y. Y. Wang, W. Zheng, Q. Luo, M. Wang and F. Y. Wang,* A Photoactive Platinum(IV) Anticancer Complex Inhibits Thioredoxin-Thioredoxin Reductase System Activity by Induced Oxidization of the Protein, Inorg. Chem. 2018, 57, 5575-5584.
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  • W. Zeng, Z. Du, Q. Luo, Y. Zhao, Y. Wang, K. Wu, F. Jia, Y. Zhang,* F. Wang*, Proteomic Strategy for Identification of Proteins Responding to Cisplatin-Damaged DNA, Anal. Chem. 2019, 91, 6035-6042. 
    Y. Zhang, Q. Luo, W. Zheng,* Z. Y. Wang, Y. Lin, E. L. Zhang, S. Lü, J. F. Xiang, Y. and F. Y. Wang*, Luminescent cyclometallated platinum(II) complexes: highly promising EGFR/DNA probes and dual-targeting anticancer agents, Inorg. Chem. Front. 2018, 5, 413-424.
  • S. Y. Liu, W. Zheng, K. Wu,* Y. Lin, F. F. Jia, Y. Zhang, Z. Y. Wang, Q. Luo, Y. Zhao, F. Y. Wang* Correlated mass spectrometry and confocal microscopy imaging verifies the dual-targeting action of an organoruthenium anticancer complex, Chem. Commum. 2017, 53, 4136-4139.
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  • Y. Y. Wang, Z. F. Du,* W.  Zheng, K. Wu, D. C. Xu, Q. Luo, Y.  Zhao, J. J. Han, Y. Z. Liu, F. Y. Wang,* Deciphering of Interactions between Platinated DNA and HMGB1 by Hydrogen/Deuterium Exchange Mass Spectrometry, Dalton Trans. 2017, 46, 6133-6484.
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  • K. Wu,  F. F. Jia, W. Zheng, Q. Luo, Y. Zhao, F. Y. Wang,* Visualization of metallodrugs in single cells by secondary ion mass spectrometry imaging, J. Biol. Inorg. Chem. 2017, 22, 653-661.
  • W. Zheng, Y. Zhao*, Q. Luo, Y.  Zhang, K.  Wu, F. Y. Wang*, Rational design of multi-targeting ruthenium- and platinum-based anticancer complexes, Sci China Chem, 2016, 59(10), 1240-1249.
  • J. Du, Y. Kang, Y. Zhao,* W. Zheng, Y. Zhang, Yu Lin, Z. Y. Wang, Y. Y. Wang, Q. Luo, Kui Wu, and F. Y. Wang,* Synthesis, Characterization, and in Vitro Antitumor Activity of Ruthenium(II) Polypyridyl Complexes Tethering EGFR-Inhibiting 4-Anilinoquinazolines, Inorg. Chem., 2016, 55, 4595-4605.
  • L. J. Li, W. Guo, K. Wu,* X. L. Wu, L. H. Zhao, Y. Zhao, Q. Luo, Y. Y. Wang, Y. Z. Liu, Q. W. Zhang, F. Y. Wang,* A comparative study on the interactions of human copper chaperone Cox17 with anticancer organoruthenium(II) complexes and cisplatin by mass spectrometry, J. Inorg. Biochem., 2016, 161, 99-106.

  • J. Du, E. L. Zhang, Y. Zhao,* W. Zheng, Y. Zhang, Y. Lin, Z. Y. Wang, Q. Luo, K. Wu, F. Y. Wang*, Dscovery of a dual-targeting organometallic ruthenium complex with high activity inducing early stage apoptosis of cancer cells, Metallomics, 2015, 7, 1573-1583.
  • Y. Zhang, W. Zheng,* Q. Luo, Y. Zhao, E. L. Zhang, S. Y. Liu, F. Y.  Wang,* Dual-targeting organometallic ruthenium(II) anticancer complexes bearing EGFR-inhibiting 4-anilinoquinazoline ligands, Dalton Trans. 2015, 44, 13100–131.

  • S. Y. Liu, K. Wu,* W. Zheng, Y. Zhao, Q. Luo, S. X. Xiong, F. Y. Wang,* Identification and Discrimination of Binding Sites of an Organoruthenium Anticancer Complex to Single-Stranded Oligonucleotides by Mass Spectrometry, Anlayst, 2014, 10.1039/c4an00807c.
  • G. J. Zhai, X. Y. Wu, Q. Luo, K. Wu, Y. Zhao, Y. L. Min, J. A. Liu, X. S. Xiong, Y. Q. Feng, L. P. Yang,* F. Y. Wang,* Absolute Quantification of Serum Phosphopeptides by Mass Spectrometry Coupled to Titania Coated Magnetic Mesoporous Silica Microsphere Enrichment, Talanta, 2014, 125, 411–417.
  • Z. Du, Q. Luo, L. Yang, T. Bing, X. Li, W. Guo, K. Wu, Y. Zhao, S. Xiong, D. Shangguan, F.-Y. Wang*, Mass Spectrometric Proteomics Reveals that Nuclear Protein Positive Cofactor PC4 Selectively Binds to Cross-Linked DNA by a trans-Platinum Anticancer Complex, J. Am. Chem. Soc. 2014, 136, 2948-2951.

  • L. Y. Ji, W. Zheng, Y. Lin, X. L. Wang, S. , X. Hao, Q. Luo,* X. C. Li, L. Yang, F. Y. Wang,* Novel Ruthenium Complexes Ligated with 4-Anilinoquinazoline Derivatives: Synthesis, Characterisation and Preliminary Evaluation of Biological Activity, Eur. J. Med. Chem. 2014, 77, 110-120
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  • S. Y. Liu, K. Wu,* W. Zheng, Y. Zhao, Q. Luo, S. X. Xiong, F. Y. Wang,* Identification and Discrimination of Binding Sites of an Organoruthenium Anticancer Complex to Single-Stranded Oligonucleotides by Mass Spectrometry, Anlayst, 2014, 10.1039/c4an00807c
  • G. J. Zhai, X. Y. Wu, Q. Luo, K. Wu, Y. Zhao, Y. L. Min, J. A. Liu, X. S. Xiong, Y. Q. Feng, L. P. Yang,* F. Y. Wang,* Absolute Quantification of Serum Phosphopeptides by Mass Spectrometry Coupled to Titania Coated Magnetic Mesoporous Silica Microsphere Enrichment, Talanta, 2014, 125, 411–417
  • W. Zheng, Q. Luo, Y. Lin, Y. Zhao, X. Wang, Z. Du, X. Hao, Y. Yu, S. Lu, L. Ji, X. Li, L. Yang, F.-Y. Wang*, Complexation with organometallic ruthenium pharmacophores enhances the ability of 4-anilinoquinazolines inducing apoptosis, Chem. Commun. 2013, 49, 10224-10226.
  • K. Wu, S. Liu, Q. Luo, W. Hu, X. Li, F.-Y, Wang*, R. Zheng, J. Cui, P. J. Sadler, J. Xiang, Q. Shi, S. Xiong, Thymines in Single-Stranded Oligonucleotides and G-Quadruplex DNA Are Competitive with Guanines for Binding to an Organoruthenium Anticancer Complex, Inorg. Chem. 2013, 52 (19), 11332-11342.
  • Y. Lin, Y-D Huang, W. Zheng, F.-Y. Wang*, A. Habtemariam, Q. Luo, X.-C. Li, K. Wu, P. J. Sadler, S.-X. Xiong, Organometallic ruthenium anticancer complexes inhibit human glutathione-S-transferase π, J Inorganic Biochem, 2013, 128, 77-84
  • W. Guo, W. Zheng, Q. Luo, X. Li, Y. Zhao, S. Xiong, F.-Y. Wang,* Transferrin Serves As a Mediator to Deliver Organometallic Ruthenium(II) Anticancer Complexes into Cells, Inorg. Chem. 2013, 52, 5328-5338.
  • K. Wu, W. Hu, Q. Luo, X. Li, S. Xiong, P. Sadler, F.-Y. Wang*, Competitive binding sites of a ruthenium arene anticancer complex on oligonucleotides studied by mass spectrometry: ladder-sequencing vs top-down, J. Am. Soc. Mass. Spectrom., 2013, 24, 410-420.
  • Qun Luo, Jianhua Cao, Daihua Tang*, Dayong Wu,Yong Huang, Junfeng Xiang, Fuyi Wang*, Xinhou Liu, Gang Wu* Lipophilic thioguanosine: an anion receptor for cesium fluorideJournal of Fluorine Chemistrypublished onlineDOI: http://dx.doi.org/doi:10.1016/j.jfluchem.2013.02.020
  • S. Lü, W. Zheng, L. Ji, Q. Luo*, X. Hao, X. Li, F.-Y. Wang*, Synthesis, characterization, screening and docking analysis of 4-anilinoquinazoline derivatives as tyrosine kinase inhibitors, Eur. J. Med. Chem. 2013, 61, 84-94.
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  • Wenbing Hu, Jianan Liu, Qun Luo*Yumiao Han, Kui Wu, Shuang Lv,  Shaoxiang Xiong, and Fuyi Wang*,. Elucidation of the Binding Sites of Sodium Dodecyl Sulfate to β-Lactoglobulin Using Hydrogen/Deuterium Exchange Mass Spectrometry Combined with Docking Simulation, Rapid Commun. Mass Spectrom., 2011, 25, 1429-1436.
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  • Qun LuoDayong Wu,  Shixiong Liu,  Daihua Tang, Yong Huang, Xinhou Liu, Fuyi Wang,  Ruiyao Wang, and Gang Wu. The formation of thymidine-based T-tetramers with remarkable structural and metal ion size effects. Organic & Biomolecular Chemistry, 2011, 9, 1030-1033
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  • Qun Luo, Daihua Tang, Gang Wu. Ribose-protected Thioguanosine-based 1H . NMR Spectroscopic Probe for the Detection of Cesium from Solid Cesium-containing Sources in Acetonitrile. Inorganic Chemistry Communications, 2008, 11 1359–1362
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  • Qun Luo, Daihua Tang, Xiaodong Li, Qi Wang, Zhipeng Wang, Zhen Zhen, and Xinhou Liu. Preparation of Polysilsesquioxane (CH3SiO1.5)8 Crystals from Swollen PHEMA. Chemistry Letters, 2006, 35(3), 278-279.
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  • Qun Luo, Daihua Tang, Zhen Zhen, and Xinhou Liu. 2’-Deoxy-3’,5’-di-O-acetyl-uridine Acta Crystallographica Section E, 2007.63 (1) .o4o6.

 

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